欧博在线登录

焦培荣

焦培荣博士生导师、硕士生导师、正高职称

 学科:预防兽医学 (动物传染病学)       
电话/传真:020-85283309         
电子邮件:prjiao@scau.edu.cn
通讯地址:广州市天河区五山路483号华南农业大学兽医欧博在线登录,510642        
教研室:传染病教研室
简介


焦培荣,博士,研究员,博士生导师,男, 1974年10月出生于内蒙古自治区鄂尔多斯市。

华南农业大学动物生物安全三级实验室安全委员会成员及禽流感项目负责人、广东省农村科技特派员。SCI学术期刊《Frontiers in Microbiology》副主编,《Journal of Immunology Research》、《Animals》和《Peer J》等SCI期刊编委及编辑。Veterinary Research、Veterinary Microbiology、International Reviews of Immunology、Poultry Science、Avian Pathology、Transboundary and Emerging Diseases、Journal of Infection、Journal of Cellular Biochemistry、Vaccine、SCIENCE CHINA Life Sciences、中国农业科学、畜牧兽医学报、中国科学:生命科学、病毒学报、中国兽医科学等20余个中英文学术期刊审稿专家。国家科技专家库评审专家(国家重点研发计划政府间国际合作重点专项会评专家、国家重点研发计划重点专项会评专家)、国家自然科学基金项目网评专家、广东\山东\河南\湖北省科技专家库专家(自然基金项目\科技计划项目等评审专家)、英国Wellcome Trust与印度DBT联合基金(The Wellcome Trust/DBT India Alliance Fellowship)项目评审专家。

主要从事禽流感等动物传染病病原学、分子流行病学、致病机制、免疫机制、宿主抗病毒天然免疫机理等研究以及动物传染病诊断、预防与控制技术与产品研发。已发表中英文学术论文120余篇,包括PNAS、Emerging Infectious Diseases、Journal of Virology、Frontiers in Immunology、Frontiers in Microbiology、Veterinary Research、Veterinary Microbiology、Veterinary Immunology and Immunopathology、Poultry Science等国际知名期刊发表SCI论文60余篇,其中以通讯作者或第一作者SCI论文38篇。Google学术统计,文章总引用次数4103、h指数24、i10指数47、单篇最高引用次数459次。申请专利15项, 授权2项。参编国内专著2部。

先后主持国家自然科学基金面上项目(3项)、十三五和十四五国家重点研发计划项目子课题、科技部国际合作项目子课题、广东省自然科学基金项目、广东省科技计划项目、广东省农业厅项目、广州市科技计划项目等各类课题20余项。先后获广东省科技奖一等奖1项、二等奖1项、三等奖1项,教育部科技进步奖二等奖1项,广东省农业技术推广一等奖1项、二等奖1项,珠海市科技进步奖二等奖2项,农业部神农中华农业科技优秀创新团队奖1项。


杂志编委


《Frontiers in Microbiology》(SCI)副主编(Associate Editor)(2022.04-至今)及编委(2014.10-至今)

《Journal of Immunology Research》(SCI)编委及编辑(2013.11-至今)

《Peer J》(SCI)编委及编辑(2014.10-至今)

《BioMed Research International》(SCI)编委及编辑 (2013.11-2017.08)

《Animals》(SCI)编委及编辑(2021.12-至今))


学历及培训经历


    2004年09月-2007年07月中国农业科欧博在线登录哈尔滨兽医研究所(国家禽流感参考实验室) 预防兽医学博士研究生

    2001年09月-2004年07月内蒙古农业大学和哈尔滨兽医研究所(国家禽流感参考实验室)  预防兽医学硕士研究生

    1995年09月-1999年07月内蒙古农业大学动物医学系 兽医专业本科


工作经历


    2018年12月-至今         华南农业大学兽医欧博在线登录 研究员

    2012年12月-2018年12月 华南农业大学兽医欧博在线登录 副研究员,硕导 (2013年)、博导(2018年)

    2013年11月-2014年11月 University of Minnesota-Twin Cities,USA 访问学者

    2008年03月-2012年12月 华南农业大学兽医欧博在线登录 助理研究员


研究领域


- 禽流感病毒病病原学、分子流行病学、致病机制、免疫机制、宿主抗病毒天然免疫机理

- 流感病毒与宿主信号通路互作机制

- 动物疫苗、动物免疫增强剂与动物疫病诊断试剂研发


承担科研项目情况

 

- 国家重点研发计划项目“动物流感病毒的流行规律与传播机制研究”课题“动物流感病毒宿主适应性机制研究”子课题“华南地区禽流感病毒的宿主适应性机制研究”。(2021YFD1800202),2021-2025,主持人

- 国家自然科学基金面上项目:禽PIAS2蛋白与禽流感病毒RNP复合体组成蛋白相互作用而影响病毒复制的分子机制,(32072844),2021-欧博在线登录,主持人

- 国家自然科学基金面上项目:禽流感病毒PB2蛋白与禽MAVS蛋白互作影响禽流感病毒致病性的分子机制。(31872497),2019-2022,主持人

- 广州市科技计划项目:H5和H7亚型禽流感新型核酸疫苗与禽用分子免疫增强剂的研制。(201904010022),2019 -2021,主持人

- 国家重点研发计划项目:“动物流感病毒遗传变异与致病机理研究”课题 “动物流感病毒免疫学研究”子课题。(2016YFD0500207),2016-2020,主持人

- 国家自然科学基金联合基金项目:RLR信号通路在禽流感病毒逃逸水禽天然免疫反应中的作用。(U1501212),2016-2019,共同负责人和主要完成人

- 广东省自然科学基金项目:RLR信号通路在禽流感病毒逃逸水禽天然免疫中的作用机理。(2016A030308001),2016-2020,共同负责人和主要完成人

- 广州市科技计划项目:高效表达的H5和H9二价禽流感核酸疫苗的研制。(201300000037),2013-2015,主持人

- 广东省农业厅项目:H7N9流感病原学研究。2014-2016,主持人

- 国家自然科学基金项目:高致病性禽流感病毒逃逸鸭1型干扰素介导的抗病毒免疫反应的机理研究。(31172343),2012-2015,主持人

- 广东省科技计划项目:高效表达的H5 和H9 亚型禽流感核酸疫苗的研制。(2012B020306003),2013-2014,主持人

- 广东省自然科学基金项目:高致病性禽流感病毒对豚鼠感染的分子机理研究。(10151064201000021),2010-2012,主持人

- 广东省科技计划项目:华南地区H5N1亚型高致病性禽流感病毒的分子流行病学及其分子致弱灭活疫苗的研究。(2010B020307005),2011-2012,主持人

- 科技部国际合作项目:“基于生物传感器的禽流感病毒快速检测技术及装备研究”项目“生物传感器检测禽流感病毒试验研究”子课题。(2010DFA31000),2010-2013,主持人

- 广东省农业厅防疫专项:禽流感变异株的流行病学调查及诊断方法的建立。2009-2011,主持人

- 广东省自然科学基金项目:高致病性禽流感跨越种间屏障传播和致病的分子机制。(8451064201001132),2008-2010,主持人


代表论著(*通讯作者)

 

1.Jianni Huang, Siyu Wu, Wenbo Wu, Yiwen Liang, Haibin Zhuang, Zhiyu Ye, Xiaoyun Qu, Ming Liao* and Peirong Jiao*. The Biological Characteristics of Novel H5N6 Highly Pathogenic Avian Influenza Virus and Its Pathogenesis in Ducks. Frontiers in microbiology. 2021; 12:628545.

2.Zuxian Chen, Zhenyu Wang, Xiya Zhao, Yun Guan, Qian Xue, Jinrong Li, Zhiting Liu, Bingbing Zhao, Zhuoliang He, Jianni Huang, Ming Liao, Yafen Song*, Peirong Jiao*. Pathogenicity of different H5N6 highly pathogenic avian influenza virus strains and host immune responses in chickens. Veterinary Microbiology.2020;246:108745.

3.Shaopo Zu, Qian Xue, Zhuoliang He, Chenxi Shi, Junsheng Zhang, Wenbo Wu, Weiqiang Li, Zhiting Liu, Jianni Huang, Peirong Jiao*, Ming Liao*. Duck PIAS2 Promotes H5N1 Avian Influenza Virus Replication Through Its SUMO E3 Ligase Activity. Frontiers in microbiology.2020;11, 1246.

4.Siyu Wu, Junsheng Zhang, Qian Xue, Jing Liu, Bingzhong Huang, Zhuoliang He, Jianni Huang, Shaopo Zu, Zuxian Chen, Bingbing Zhao, Ming Liao*, Peirong Jiao*. Duck TRIM32 Functions in IFN-β Signaling Against the Infection of H5N6 Highly Pathogenic Avian Influenza Virus. Frontiers in Immunology. 2020; 11: 377.

5.Siyu Wu, Jianni Huang, Qiwen Huang, Junshen Zhang, Jing Liu, Qian Xue, Weiqiang Li, Ming Liao*, Peirong Jiao*. Host Innate Immune Response of Geese Infected with Clade 2.3.4.4 H5N6 Highly Pathogenic Avian Influenza Viruses. Microorganisms. 2020;8(2):224.

6.Yafen Song, Weiqiang Li, Wenbo Wu, Zhiting Liu, Zhuoliang He, Zuxian Chen, Bingbing Zhao, Siyu Wu, Chenghuai Yang, Xiaoyun Qu, Ming Liao*, and Peirong Jiao*. Phylogeny, Pathogenicity, Transmission, and Host Immune Responses of Four H5N6 Avian Influenza Viruses in Chickens and Mice. Viruses. 2019; 11(11):1048.

7.Hao Yu, Kunpeng Zhang, Xumeng Ye, Wenqing Wang, Wenbo Wu, Xia Wang, Yun Guan, Zuoliang He, Yong Wang* and Peirong Jiao*. Comparative Pathogenicity and Transmissibility of the H7N9 Highly Pathogenic Avian Influenza Virus and the H7N9 Low Pathogenic Avian Influenza Virus in Chickens. Viruses. 2019; 11(11):1047.

8.Nannan Qu, Bingbing Zhao, Zuxian Chen, Zhuoliang He, Weiqiang Li, Zhiting Liu, Xia Wang, Jianni Huang, You Zhang, Wanting He, Jie Sun, Zhifeng Qin, Ming Liao, Peirong Jiao*. Genetic characteristics, pathogenicity and transmission of H5N6 highly pathogenic avian influenza viruses in Southern China. Transbound Emerg Dis. 2019; 00:1-15.

9.Siyu Wu, Junsheng Zhang, Jianni Huang, Weiqiang Li, Zhiting Liu, Zhuoliang He, Zuxian Chen, Wanting He, Bingbing Zhao, Zhifeng Qin, Peirong Jiao* and Ming Liao*. Immune-Related Gene Expression in Ducks Infected with Waterfowl-Origin H5N6 Highly Pathogenic Avian Influenza Viruses. Front Microbiol.2019, 10:1782.

10.Kun Mei, Yang Guo, Xuhui Zhu, Nannan Qu, Jianni Huang, Zuxian Chen, You Zhang, Bingbing Zhao, Zhuoliang He, Ming Liao* and Peirong Jiao*. Different Pathogenicity and Transmissibility of Goose-Origin H5N6 Avian Influenza Viruses in Chickens. Viruses. 2019, 11; 612.

11.Jiao P, Song Y, Huang J, Xiang C, Cui J, Wu S, Qu N, Wang N, Ouyang G, Liao M*.H7N9 Avian Influenza Virus Is Efficiently Transmissible and Induces an Antibody Response in Chickens. Front Immuno.9: 789,2018.

12.Wang N, Sun M, Wang W, Ouyang G, Chen Z, Zhang Y, Zhao B, Wu S, Huang J, Sun H, Liao M*, Jiao P*. Avian Influenza (H7N9) Viruses Co-circulating among Chickens, Southern China. Emerg Infect Dis. 23(12):2100-2102,2017.

13.Cui J, Qu N, Guo Y, Cao L, Wu S, Mei K, Sun H, Lu Y, Qin Z, Jiao P*, Liao M*. Phylogeny, Pathogenicity, and Transmission of H5N1 Avian Influenza Viruses in Chickens. Front Cell Infect Microbiol. 19; 7:328,2017.

14.Wei L, Song Y, Cui J, Qu N, Wang N, Ouyang G, Liao M, Jiao P*. Cloning, characterization, and expression analysis of LGP2 cDNA from goose, Anser cygnoides. Poult Sci. 95(10):2290-6,2016.

15.Song Y, Wu X, Wang N, Ouyang G, Qu N, Cui J, Qi Y, Liao M, Jiao P*. A Novel H1N2 Influenza Virus Related to the Classical and Human Influenza Viruses from Pigs in Southern China. Front Microbiol. 8; 7:1068,2016.

16.Jiao P, Cui J, Song Y, Song H, Zhao Z, Wu S, Qu N, Wang N, Ouyang G, Liao M*. New Reassortant H5N6 Highly Pathogenic Avian Influenza Viruses in Southern China, 2014. Front Microbiol. 19; 7:754,2016.

17.Jiao P, Song H, Liu X, Song Y, Cui J, Wu S, Ye J, Qu N, Zhang T, Liao M*. Pathogenicity, Transmission and Antigenic Variation of H5N1 Highly Pathogenic Avian Influenza Viruses. Front Microbiol. 6; 7:635,2016.

18.Song Y, Cui J, Song H, Ye J, Zhao Z, Wu S, Xu C, Jiao P* and Liao M*. New reassortant H5N8 highly pathogenic avian influenza virus from waterfowl in Southern China. Front Microbiol. 23; 6:1170,2015. 

19.Jiao PR, Wei LM, Song YF, Cui J, Zhang S, Han F, Yuan RY, Liao M*. Molecular cloning and immune responsive expression of LGP2 gene, a pivotal member of the RLR gene family from Muscovy duck Cairina moschata. Poult Sci. 94(6):1170-6,2015.

20.Sun H, Cui P, Song Y, Qi Y, Li X, Qi W, Xu C, Jiao P* and Liao M*.PB2 segment promotes high-pathogenicity of H5N1 avian influenza viruses in mice. Front Microbiol. 10; 6:73,2015.

21.Jiao P, Wei L, Song Y, Cui J, Song H, Cao L, Yuan R, Luo K, Liao M*. D701N mutation in the PB2 protein contributes to the pathogenicity of H5N1 avian influenza viruses but not transmissibility in guinea pigs. Front Microbiol. 25; 5:642,2014. 

22.Kang Y, Li Y, Yuan R, Li X, Sun M, Wang Z, Feng M, Jiao P*, Ren T*. Phylogenetic relationships and pathogenicity variation of two Newcastle disease viruses isolated from domestic ducks in Southern China. Virol J. 12; 11:147,2014. 

23.Wei L, Cui J, Song Y, Zhang S, Han F, Yuan R, Gong L, Jiao P*, Liao M*. Duck MDA5 functions in innate immunity against H5N1 highly pathogenic avian influenza virus infections. Vet Res. 18; 45:66,2014.

24.Yuan R, Cui J, Zhang S, Cao L, Liu X, Kang Y, Song Y, Gong L, Jiao P*, Liao M*. Pathogenicity and transmission of H5N1 avian influenza viruses in different birds. Vet Microbiol. 10;168(1):50-9,2014.

25.Wei LM#, Jiao PR#, Song YF, Han F, Cao L, Yang F, Ren T, Liao M*. Identification and expression profiling analysis of goose melanoma differentiation associated gene 5 (MDA5) gene. Poult Sci. 92(10):2618-24,2013. (#并列第一)

26.Wei L#, Jiao P#, Song Y, Cao L, Yuan R, Gong L, Cui J, Zhang S, Qi W, Yang S, Liao M*. Host immune responses of ducks infected with H5N1 highly pathogenic avian influenza viruses of different pathogenicities. Vet Microbiol. 25;166(3-4):386-93,2013.

27.Wei L#, Jiao P#, Yuan R, Song Y, Cui P, Guo X, Zheng B, Jia W, Qi W, Ren T, Liao M*. Goose Toll-like receptor 7 (TLR7), myeloid differentiation factor 88 (MyD88) and antiviral molecules involved in antiH5N1 highly pathogenic avian influenza virus response. Vet Immunol Immunopathol. 15;153(1-2):99-106,2013.

28.Jiao P, Wei L, Cheng Y, Yuan R, Han F, Liang J, Liu W, Ren T, Xin C, Liao M*. Molecular cloning, characterization, and expression analysis of the Muscovy duck Toll-like receptor 3 (MdTLR3) gene. Poult Sci. 91(10):2475-81,2012.

29.Jiao P, Song Y, Yuan R, Wei L, Cao L, Luo K, Liao M*. Complete Genomic Sequence of an H5N1 Influenza Virus from a Parrot in Southern China. J Virol. 86(16):8894-5,2012. 

30.Jiao P, Wei L, Yuan R, Gong L, Cao L, Song Y, Luo K, Ren T, Liao M*. Complete Genome Sequence of an H5N2 Avian Influenza Virus Isolated from a Parrot in Southern China. J Virol. 86(16):8890-1,2012. 

31.Jiao P, Wei L, Yuan R, Song Y, Cao L, Liao M*. Complete Genome Sequence of an H7N3 Avian Influenza Virus Isolated from Ducks in Southern China. J Virol. 86(14):7724-5,2012.

32.Jiao P, Yuan R, Song Y, Wei L, Ren T, Liao M, Luo K*. Full Genome Sequence of a Recombinant H5N1 Influenza Virus from a Condor in Southern China. J Virol. 2012 Jul;86(14):7722-3.

33.Jiao P, Yuan R, Wei L, Jia B, Cao L, Song Y, Gong L, Xu C, Ren T, Liao M*. Complete Genomic Sequence of a Novel Natural Recombinant H6N2 Influenza Virus from Chickens in Guangdong, Southern China. J Virol. 86(14):7717-8,2012.

34.Jiao P, Cao L, Yuan R, Wei L, Song Y, Shen D, Gong L, Luo K, Ren T, Liao M*. Complete Genome Sequence of an H10N8 Avian Influenza Virus Isolated from a Live Bird Market in Southern China. J Virol. 86(14):7716,2012.

35.Sun H#, Jiao P#, Jia B, Xu C, Wei L, Shan F, Luo K, Xin C, Zhang K, Liao M*. Pathogenicity in quails and mice of H5N1 highly pathogenic avian influenza viruses isolated from ducks. Vet Microbiol. 28;152(3-4):258-65,2011.

36.S Li#, Z Shi#, P Jiao#, G Zhang, Z Zhong, W Tian, LP Long, Z Cai, X Zhu, M Liao, and XF Wan*. Avian-origin H3N2 canine influenza A virus in Southern China. Infect Genet Evol. 10(8):1286-8,2010.

37.Jiao P, Tian G, Li Y, Deng G, Jiang Y, Liu C, Liu W, Bu Z, Kawaoka Y, Chen H*. A single amino acid substitution in the NS1 protein changes the pathogenicity of H5N1 avian influenza viruses in mice. J Virol. 82(3):1146-54,2008. (Spotlight Article of JVI and Highlight Article of Microbe)

38.Li Z, Jiang Y, Jiao P, Wang A, Zhao F, Tian G, Wang X, Yu K, Bu Z, Chen H*. The NS1 gene contributes to the virulence of H5N1 avian influenza viruses. J Virol. 80(22):11115-23,2006.

39.Li Z, Chen H, Jiao P, Deng G, Tian G, Li Y, Hoffmann E, Webster RG, Matsuoka Y, Yu K. Molecular basis of replication of duck H5N1 influenza viruses in a mammalian mouse model.J Virol. 79(18):12058-64,2005.

40.Chen H, Deng G, Li Z, Tian G, Li Y, Jiao P, Zhang L, Liu Z, Webster RG, Yu K*. The evolution of H5N1 influenza viruses in ducks in southern China. Proc Natl Acad Sci U S A. 13;101(28):10452-7,2004.

41.叶芷羽,李伟强,刘智婷,庄海彬,车斯琪,陈治濠,欧阳婷,王蕊,焦培荣. 马岗鹅RIG-Ⅰ基因扩增及序列分析[J]. 中国家禽, 2021, 43(12): 26-32.

42.曲楠楠,陈祖贤,赵冰兵,李伟强,刘智婷,王霞,何婉婷,瞿孝云,焦培荣.鸡TRIM25蛋白可促进宿主对禽流感病毒的天然免疫应答[J].中国科学:生命科学,2018,48(12):1273-1278.

43.王霞,何婉婷,李伟强,刘智婷,王文清,张友,陈祖贤,赵冰兵,廖明,焦培荣.当前我国H7N9亚型禽流感状况分析[J].动物医学进展,2018,39(09):126-129.

44.李伟强,何婉婷,王霞,刘智婷,张友,王文清,赵冰兵,陈祖贤,廖明,瞿孝云,焦培荣.当前我国H5亚型禽流感的流行情况及防控对策[J].中国兽医杂志,2018,54(02):114-116. 

45.刘智婷,李伟强,王霞,何婉婷,张友,王文清,陈祖贤,赵冰兵,廖明,焦培荣.当前全球禽流感流行状况与流行特点分析[J].中国家禽,2017,39(24):1-4.

46.吴斯宇,黄健妮,崔进,冯赛祥,欧阳国文,向程威,郭旸,廖明,焦培荣*. 鸡β干扰素的原核表达及抗病毒活性检测[J]. 中国动物传染病学报,2016,04:59-63. 

47.王念晨,曲楠楠,欧阳国文,赵冰兵,陈祖贤,张友,王文清,吴斯宇,廖明,焦培荣*. 当前我国H5亚型高致病性禽流感流行情况分析[J]. 中国动物传染病学报,2016,04:77-81. 

48.吴斯宇,孙超,崔进,冯赛祥,黄健妮,王念晨,曲楠楠,廖明,焦培荣*. 鸡α干扰素的原核表达及纯化[J]. 中国兽医杂志,2016,08:29-31.

49.张烁,林宏文,袁润余,宋亚芬,崔进,龚浪,瞿孝云,韩翡,吴晓薇,徐成刚,廖明,焦培荣*.H6N6亚型禽流感病毒广东分离株分子遗传演化分析.畜牧兽医学报, 45(6):989-996, 2014.

50.韩翡, 焦培荣*, 韦良孟, 何静, 宋亚芬, 康银峰, 廖明,任涛*. 鸽TLR7 基因的克隆, 鉴定及表达分析. 华南农业大学学报, 35(3):18-23, 2014.

51.程玉强,焦培荣*,韦良孟,钟自富,廖顺娣,袁润余,贾宝琴,罗开。蚊*.鸭RIG-I基因的PCR扩增及其序列分析.动物医学进展, 33(6):15-21, 2012.

52.李泽君,焦培荣,于康震,陈化兰*.H5N1亚型高致病性禽流感病毒A/Goose/Guangdong/1/96株反向基因操作系统的建立.中国农业科学, 38(8):1686-1690, 2005.

53.焦培荣、廖明.病毒-宿主相互作用(第四章),p215-226. 禽流感/于康震、陈化兰主编.中国农业出版社.2015年,北京.


写给学生的话
 

    

踏实做人,认真做事!


欧博在线登录 - 搜狗指南